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Anisole

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  • Anisole, or Methoxybenzene, is the organic compound with the formula CH3OC6H5. It is a colorless liquid with a smell reminiscent of anise seed, and in fact many of its derivatives are found in natural and artificial fragrances.

  • It is a straw-colored to colorless liquid with an agreeable spicy-sweet odor. It is used in perfumes, as a flavoring in food and in the manufacture of other chemicals.

  • Anisole undergoes electrophilic aromatic substitution reaction more quickly than does benzene, which in turn reacts more quickly than nitrobenzene.

  • Anisole is miscible in ethanol, yielding a clear, colorless solution. It is also miscible in ether.

  • Anisole is prepared by the Williamson ether synthesis, reacting sodium phenoxide with methyl bromide and related methylating reagents.

  • The manufacture of anisole in which phenol and dimethylether are continuously brought together as reactants in the vapor phase and contacted with a dehydrating catalyst.

  • Anisole is a solvent used in the synthesis of organic compounds and in large-scale applications such as the production of perfumes.

  • It has been used directly in the synthesis of the marine pyrrole alkaloids polycitone A and B and the nonylphenol isomer.

  • Anisole is frequently used in the solid-phase synthesis of compounds, particularly in the cleavage of compounds from the resin such as phosphopepties.

  • Anisole is a precursor to perfumes, insect pheromones, and pharmaceuticals.

  • The use of anisole as a scavenger along with an extended incubation period may result in higher protein recovery and more protection for amide bonds and side chains.

  • Phenol, DMC and catalyst are fed to the PMC reaction section where a small amount of anisole and CO2 are also produced.

  • It has been reported that a free-radical scavenger species-anisole may neutralize reactive groups formed during the reaction.

  • A novel anisole mixture containing anisole and a mixture of alkyl anisoles and liquid hydrocarbon fuels containing said novel anisole mixture in an amount sufficient to increase the octane number of said liquid fuel composition.

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