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  • Aristolochic acids are a family of carcinogenic, mutagenic, and nephrotoxic compounds commonly found in the Aristolochiaceae family of plants, including Aristolochia and Asarum, which are commonly used in Chinese herbal medicine.
  • Aristolochic acid I is the most abundant of the aristolochic acids and is found in almost all Aristolochia species.
  • Aristolochic acids are slightly soluble in water, have a melting point between 281 and 286 degrees Celsius, and have a bitter flavor.
  • Aristolochic acids may be a causative agent in Balkan nephropathy.
  • Plants containing aristolochic acids are often used as herbal medicines or in other botanical products in the United States and abroad.
  • Aristolochic acids may be found as a contaminant in herbal products used to treat a wide variety of symptoms and diseases, such as arthritis, gout, and inflammation.
  • Aristolochic acid (AA), a mixture of aristolochic acid I (AAI) and aristolochic acid II (AAII), is present in Aristolochiaceae plants, many of which are used as herbal folk remedies.
  • A facile reversed-phase HPLC method for the analysis of aristolochic acid (AA) and aristolactam (AL) analogues was developed and used for the quantitative determination and quality control of the traditional Chinese medicine.
  • Aristolochia spp. and Asarum spp. are widely used in traditional Chinese medicine (TCM), but those products are regulated as medicines in Taiwan.
  • A reversed-phase high performance liquid chromatographic method was established for the quantitative determination of aristolochic acid in different parts of Asarum heterotropoides produced in different places and growing years.
  • Aristolochic acids are a family of acids found naturally in the plants Aristolochia and Asarum, which grow throughout the United States and worldwide.

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