Bovine Placenta Products

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  • The bovine placenta produces a wide variety of proteins that are structurally and functionally similar to the pituitary proteins from the GH/PRL gene family.

  • Bovine placental lactogen (bPL) is a 200-amino acid long glycoprotein hormone that exhibits both lactogenic and somatogenic properties.

  • Placental extracts have long been used as an active ingredient for skin lightening QDs, together with ascorbic acid and its derivatives. Previously, a bovine-derived placental extract was the primary commercial source. However, swine-derived placental extracts are now used because of concern over mad cow disease.

  • Various amino acids and minerals are at high concentrations in placental extracts, and the efficient inhibition of melanin synthesis and the enhancement of melanin removal from the skin, due to increased epidermal turnover have been reported.

  • Interestingly, although placental extract has a strong history of use to decrease hyper pigmentation, it has also been shown to increase melanogenesis. The lipid fraction of human placental extract was reported to increase melanin synthesis via the enhancement of tyrosinase gene expression.

  • A growth factor found in the placenta of mammals. This factor can stimulate cellular division of blood vessels and increase the permeability of some cell layers found in blood vessels and the lymphatics.

  • Placenta wrinkle cream derived from bovine placentas can slow down the appearance of visible signs of aging by moisturizing skin and combating wrinkles.

  • The bovine placenta produces large amounts of steroids, mainly estrone (E1) and progesterone (P4). Specific features of bovine placental steroidogenesis are 1) the expression of all enzymes needed for the production of estrogens from cholesterol in the trophoblast 2) an only marginal and temporal contribution to peripheral maternal P4 levels restricted to a period between approx. days 150 - 240 of gestation 3) the predominance of sulfoconjugated over free E1 and 4) a complementary setting of
    steroidogenic enzymes in the two morphologically discriminable trophoblast cell types, the uninucleated trophoblast cells (UTC) and the trophoblast giant cells (TGC).

  • The Placenta Extract used in Hask products is from bovine placenta (cow), collected after the natural birthing process in its purest and most stable form of Lyophilized Powder. The powder is then reconstituted with deionized water or oils for use in Hask products.

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