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Information @ a Glance


  • The isosorbide is a heterocyclic compound obtained from reaction of the double dehydration of sorbitol , which is itself
    derived from the reaction of hydrogenation of glucose.
  • Isosorbide is a diol derived from agricultural resources, non toxic, biodegradable and thermally stable.
  • The isosorbide is a monomer that can be inserted into the macromolecular chains of type polymers (polycarbonates,
    polyurethanes, polyesters ...). It is also used for the synthesis of derivatives such as diesters, diethers, dinitrates.
  • The isosorbide is considered synthon providing access to a new platform chemical of interest because it is derived from the plant and provides many derived properties equal or superior to their counterparts in the petrochemical industry.
  • The isosorbide is a white solid soluble in water, alcohols and ketones and almost insoluble in hydrocarbons , the ethers and  esters.
  • The isosorbide is very hygroscopic , that is to say, it tends to absorb moisture from environmental absorption or adsorption.
  • The isosorbide is non-toxic and heat stable. This molecule does not break down that from 270 C in the absence of oxygen.
  • Isosorbide is a used as a diuretic used mainly to treat hydrocephalus and is also used to treat glaucoma.
  • Other medications are derived from isosorbide, including isosorbide dinitrate and isosorbide mononitrate, are used to treat angina pectoris. Other isosorbide-based medicines are used as osmotic diuretics and for treatment of esophageal varices.
  • Isosorbide is used to prevent or treat chest pain (angina). It works by relaxing the blood vessels to the heart, so the blood and oxygen supply to the heart is increased.
  • Isosorbide is a polmer component or additive that can significantly improve the performance characteristics of plastics.
  • The advantage of isosorbide is that it can raise the use temperature and performance for moldable plastics.
  • Isosorbide has been demonstrated to be a very effective monomer for raising the glass transition temperature of polymers. The major applications are as a copolymer with PET for the use in bottle production.
  • The use of biobased isosorbide as a polymer additive has the potential to reduce the amount of petroleum feedstocks used in the polymer industry, lower emissions (e.g., carbon dioxide), and offer a higher value-added alternative for corn growers and other agribusinesses.
  • Isosorbide can be substituted for other diols in order to create new polyesters, polycarbonates and polyurethanes that are
    partially or even completely bio-based.
  • Interest in the production of isosorbide has been generated by recent discoveries of the effects of co-polymerizing isosorbide with polymers such as polyethylene terephthalate (PET). When isosorbide is added to PET, the co-polymer, sPET, is stronger and more rigid than the original PET. PET is used in a variety of food and beverage containers with a current market of 4.4 billion pounds.

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