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 N,N-DIMETHYLANILINE

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  • N,N-Dimethylaniline (DMA) is an organic chemical compound, a substituted derivative ofaniline.
  • It consists of a tertiary amine, featuring dimethylamino group attached to a phenylgroup. This oily liquid is colourless when pure, but commercial samples are often yellow.
  • DMA is produced industrially by alkylation of aniline with methanol in the presence of an acid catalyst Similarly, it is also prepared using dimethyl ether as the methylating agent.
  • N,N-Dimethylaniline (DMA) is colourless or pale yellow to brown, oily liquid with characteristic amine-like odor. DMA is less dense than water and insoluble in water.
  • Freely soluble in alcohol, acetone, benzene, chloroform, diethyl ether, ethanol and acid solution. Stable under ordinary conditions of use and storage.
  • N,N-Dimethylaniline is used in the manufacture of Michler's ketone which is a chemical intermediate used in the synthesis of many dyes and pigments, particularly auramine derivatives. These pigments are used to dye paper, textiles, and leather.
  • The main types of the dyes that can be manufactured from DMA are alkali light yellow, alkali purple 5BN, alkali light green, alkali turquoise blue, bright red 5 GN, bright blue.
  • N,N-Dimethylaniline is a key precursor to commercially important triarylmethane dyes such as Malachite green or Crystal (Gentian) violet used as a histological stain and in Gram's method of classifying bacteria.
  • N,N-Dimethylaniline serves as a promoter in the curing of polyester and vinyl ester resins.
  • DMA is used as a stabilizer for colorimetric peroxidase determination.
  • Fragrance-N,N-Dimethylaniline is used as an intermediate to manufacture vanillin.
  • Pharma-DMA is used to manufacture cephalosporin V, madribon, flucytosine and sulphormethoxine in medical industry.
  • Excess exposure to N,N-dimethylaniline affects the ability of the blood to carry oxygen. The earliest visible effect may be a bluish color of the skin, especially the lips. If the lack of oxygen becomes severe, a person may experience drowsiness, headache, nausea, and vomiting .

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