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  • Phloroglucinol is a benzenetriol. It is an organic compound that is used in the synthesis of pharmaceuticals and explosives.
  • From water, phloroglucinol crystallizes as the dihydrate, which has a melting point of 116117 C, but the anhydrous form melts much higher, at 218220 C. It does not boil intact, but it does sublime.
  • Phloroglucinol was originally isolated from bark of fruit trees.
  • It is used in as a reagent for pentoses, pentosans, glycuronates, hydrochloric acid in gastric juice
  • It is an excellent bone decalcifying agent and a floral preservative.
  • They are used as chemical intermediate to synthesis target molecules of pharmaceuticals, pesticides, stabilizer, antioxidant, colorants, perfumes, photoinitiators, and other organic compounds.
  • Natural Occurence :-Phloroglucinols occur naturally in certain plant species. For example, they (and sometimes their acyl dervatives) are present in the fronds of the coastal woodfern, Dryopteris arguta.
  • Brown algae also produce phloroglucinol derivatives known as phlorotannins.
  • Metabolism :- Phloretin hydrolase uses phloretin and water to produce phloretate and phloroglucinol.
  • Application :- Phloroglucinol is mainly used as a coupling agent in printing. It links diazo dyes to give a fast black.
  • It is useful for the industrial synthesis of pharmaceuticals, cosmetics, textiles, paints dyeing industries and explosives.
  • It is also used as a treatment for gallstones, spasmodic pain and other related gastrointestinal disorders.
  • It has a non-specific spasmolytic action on the vessels, bronchi, intestine, ureters and gall bladder, and is used for treating disorders of these organs.
  • Phloroglucinolysis is an analytical technique to study condensed tannins by mean of depolymerisation. The reaction makes use of phloroglucinol as nucleophile.
  • Phloroglucinol Is Slightly Soluble In Water
  • Pholoroglucinol Is White To Yellowish White Crystalline Powder
  • Phloroglucinol is used usually to treat spasms or pain during pregnancy. This medicine is usually tolerable both by baby and mother with minimal side effects like rashes, urticaria which can be treated symptomatically.

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