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  • Capsidiol is a terpenoid compound that accumulates in tobacco Nicotiana tabacum and chili pepper Capsicum annuum in response to fungal infection.

  • Capsidiol is categorized under the broad term of phytoalexin, a class of low molecular weight plant secondary metabolites that are produced during infection.

  • Capsidiol is produced in the pepper fruit Capsicum annuum or tobacco Nicotiana tabacum after infection by the oomycete water-mold Phytophthora capsici.

  • In pepper or tobacco fields, the fungus is soil-borne and initially infects roots, collars and lower leaves. Sporangia are moved within fields by contact with field equipment, clothing, gloves, tools etc. and initial infections spread zoospores through splashing of water from irrigation or rain.

  • Capsidiol is a bicyclic terpene that is biosynthetically derived from the mevalonate pathway via farnesyl pyrophosphate (FPP). Exogenous treatment with H2O2 alone has been shown to induce capsidiol production. Capsidiol production is then increased in response to radical oxygen species

  • The sweet pepper phytoalexin capsidiol is metabolized to an appreciable extent by healthy pepper tissue.

  • Capsidiol, a sesquiterpene is produced by peepers in response to infection with a range of fungi and has many of the properties postulated for phytoalexins.

  • In pepper and tobacco, the bicyclic sesquiterpene capsidiol represents the main type ofphytoalexin.

  • Capsidiol is synthesized from farnesyl diphosphate via a two-step process catalyzed by 5-epi-aristolochene synthase and 5-epi-aritolochene hydroxylase.

  • In Wild type plants the biosynthesis of capsidiol is accompanied by decreased bioactive abscisic acid.

  • Incorporation of radioactivity from acetate into capsidiol was reduced following elicitor treatment of a trichodiene-producing transformant as compared with wild type.

  • It is a fungitoxic sesquiterpenoid that is produced in tobacco cell-suspension cultures in response to specific elicitors.

  • Capsidiol accumulation for AgNo3 in the callus tissues was higher than the accumulation in the filtrat. But CuSo4 caused more capsidiol accumulation in the filtrat than the tissue.

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