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- Edible vaccines are
composed of antigenic proteins and do not contain pathogenic genes
(because obviously they use attenuated strains).
- Development of edible
vaccines is a possible high-volume, low-cost delivery system for
third-world countries to fight against fatal maladies like AIDS,
hepatitis and diarrhea.
- Edible vaccines hold
great promise as a cost-effective, easy-to-administer,
easy-to-store, fail-safe and socioculturally readily acceptable
vaccine delivery system, especially for the poor developing
countries.
- Edible vaccines are
sub-unit vaccines that introduce selected genes into the plants and
facilitate the production of the encoded protein.Edible vaccines are
mucosal-targeted vaccines that stimulate both the systematic and
mucosal immune network takes place.
- Edible plants, rather
than tobacco, are now in the focus of research targeted at HBV
vaccine production in plants.
- Exploiting plants as
biological bioreactors for production and delivery of edible oral
subunit vaccines is a promising application of biotechnology.
- Edible plants
producing immunogens are likely to become the delivery vehicles of
choice for future vaccines.
- Edible vaccine fight
against bovine pneumonic pasteurellosis, or shipping fever. It is
estimated that shipping fever causes an annual loss of over $1
billion in North America as a result of treatment costs, labour,
reduced weight gain, poor feed conversion, poor carcass quality and
animal deaths.
- Edible vaccines are
prepared by molecular farming using the science of genetic
engineering.
- An effective oral
immunisation protocol applicable for edible vaccines for which the
frequency of feeding is limited by the maximal possible oral intake.
- Genetically modified
tomatoes containing edible vaccine coule be used against two of the
world's most lethal viruses - HIV and hepatitis B. They would help
create cheap vaccines which could be grown and processed in poorer
countries that need them most but cannot afford to make existing
vaccines.
- About 2 billion people
in the world are infected by the hepatitis B virus. Human
Papillomaviruses (HPV) are the causative agents for cervical cancer,
being also involved in skin, head and neck tumors.
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