Hydromorphone                                                                            Pharmaceutical, Uses, Analysis, Process, Patent, Consultants, Suppliers, Report                                                           Primary Information Services                                                            Home. Ordering Information. Contact        

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  • Hydromorphone, a more common synonym for dihydromorphinone, commonly a hydrochloride is a very potent centrally-acting analgesic drug.
  • Hydromorphone (Dilaudid®) belongs to a class of drugs called opioids which includes morphine.
  • Hydromorphone may cause constipation, pupillary constriction, urinary retention, nausea, vomiting and respiratory depression.
  • Hydromorphone is legally manufactured and distributed in the United States.
  • It is considered the strongest of the antitussive drugs, and was developed shortly after diacetylmorphine (heroin) was removed from clinical use.
  • Hydromorphone is used to relieve moderate to severe pain and severe, painful dry coughing.
  • Hydromorphone was first synthesized and researched in Germany.
  • Hydromorphone is known in various countries around the world by the trade names Hydal, Dimorphone, Sophidone LP, Dilaudid, Hydrostat, Hydromorfan, Hydromorphan, Hymorphan, Laudicon, Hymorphan, Opidol, Palladone, and others.
  • Hydromorphone hydrochloride (anhydrous) is the salt used in virtually all hydromorphone products and in prescription compounding at this time.
  • Although hydromorphone is a very good pain killer it is not helpful for all types of pain.
  • A GC/MS method suitable to conduct practical toxicological analyses of unspecified opiates including hydrocodone or hydromorphone. Silylation can be a convenient reaction to derivatize unknown analytes in toxicological samples.
  • Patient-controlled analgesia (PCA) is a widely used delivery system for intravenous (IV) administration of opioids during acute post-operative pain management. Various opioids have been used for IV PCA including morphine, meperidine, hydromorphone, and fentanyl.
  • The morphine alkaloid hydromorphone (dihydromorphinone) was identified as an intermediary metabolite in the degradation of morphine by Pseudomonas putida M10.
  • Hydromorphone can be used as a premedication, alone or in combination with tranquilizers or sedatives; as part of an induction regime for high-risk patients; and as an analgesic in the perianesthetic period.

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