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Information @ a Glance

General Information

  • MCPA or 2-methyl-4-chlorophenoxyacetic acid is a powerful, selective, widely-used phenoxy herbicide. The pure compound is a brown-colored powder.
  • MCPA does not dissolve well in water, but is soluble in organic (carbon-containing) solvents. MCPA is usually sold commercially in solution with organic solvents. Physical and toxicological properties are dependent on the nature of the solvent used.


  • Capillary zone electrophoresis (CZE) with diode array detection was successfully used for the analysis of 2-methyl-4-chlorophenoxyacetic acid (MCPA) herbicide in an aqueous commercial plant protection product.
  • Plasmid pJP4 is an 80-kilobase, IncPl, broad-host-range coWugative plasmid of Alckligenes eutrophus encoding resistance to mercuric chloride and phenyl mercury acetate and degradation of 2,4-dichlorophenoxyacetic acid, 2-methyl-4-chlorophenoxyacetic acid, and 3-chlorobenzoate.
  • The mecoprop-degrading community could also degrade 2,4-dichlorophenoxyacetic acid and 2-methyl-4-chlorophenoxyacetic acid but not 2,4,5-trichlorophenoxyacetic acid.

Application & Report

  • 2-Methyl-4-chlorophenoxyacetic acid (MCPA) is a widely used phenoxyalkanoic acid herbicide and subject to aerobic microbial degradation.
  • Earthworms stimulate both growth and activity of MCPA-degrading bacteria in soil.
  • M.C.P.A. (2-methyl-4-chlorophenoxyacetic acid) is one of the recently developed hormone weed-killers and is freely available without control.
  • The mortality and cancer incidence of employees at a company which has manufactured, formulated, and sprayed 2 methyl-4 chlorophenoxyacetic acid (MCPA) and other phenoxy acid herbicides.

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