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Information @ a Glance

General

  • The chemical compound acrylamide (acrylic amide) has the chemical formula C3H5NO. Its IUPAC name is 2-propenamide.
  • Acrylamide is a white odourless crystalline solid, soluble in water, ethanol, ether and chloroform.
  • Acrylamide is incompatible with acids, bases, oxidizing agents, iron and iron salts.
  • It decomposes non-thermally to form ammonia and thermal decomposition produces carbon monoxide, carbon dioxide and oxides of nitrogen.
     

Process

  • Polyacrylamide particles containing nanosized magnetic iron oxide were prepared via inverse miniemulsion polymerization.
  • Inverse miniemulsion polymerization was adopted to synthesize the magnetic polyacrylamide particles using small molecular emulsifier.
  • The current industry or government accepted method for acrylamide is based on LC/MS/MS (high performance liquid chromatography/tandem mass spectrometry).
  • Thermal polymerization of acrylamide was studied by differential scanning calorimetry.

Applications

  • Acrylamide also has many other uses in the modern molecular biology laboratory, including the use of linear polyacrylamide (LPA) as a carrier.
  • LPA aids in the precipitation of small amounts of DNA. Many laboratory supply companies sell LPA as a commercial product.
  • Most acrylamide is used to synthesize polyacrylamides which find many uses as water-soluble thickeners.
  • Acrylamide is used in the manufacture of dyes and the manufacture of other monomers.
  • Polyacrylamide (PAAm) gel is one of the most popular gels in the field of protein separation or medical applications.


Report

  • Acrylamide is a large volume industrial chemical used mainly in the manufacture of water-soluble polymers.
  • This widespread public exposure to acrylamide was taken as a concern by competent authorities worldwide.
  • Acrylamide has been classified as probable human carcinogenic compound by the International Agency for Research on Cancer (IARC).
  • The toxic effects of acrylamide on the nervous system in humans following high occupational and accidental exposures.

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