- Albendazole, marketed
as Albenza, Eskazole or Zentel.
- Albendazole is a
member of the benzimidazole compounds used as a drug.
- Albendazole also has
been shown to inhibit the enzyme fumarate reductase, which is helminth-specific.
- Albendazole is
approved in several European and most Third World countries.
- Albendazole works
really well against one called Septata.
- Albendazole is a
- Albendazole is white
to yellowish crystalline powder.
- Albendazole (ABZ) is
oxidized to a sulfoxide (ABZSO), which is in part further oxidized to a
sulfone (ABZSO2); albendazole sulfoxide is the main metabolite in vivo.
- The formation of
ABZSO is directly associated with two different microsomal enzymatic
systems, cytochrome P-450 and flavin-containing monooxygenase (FMO).
- The selective
S-oxidation of albendazole, fenbendazole, and other benzimidazole
sulfides with sodium periodate in acid medium, afforded the
corresponding sulfoxides or sulfones.
- Sensory Analysis was
used in the albendazole suspension stability study.
- A meta-analysis of
randomized trials compares the effect of albendazole and praziquantel
with no specific therapy to evaluate the effect of cysticidal drug
therapy on complete destruction of active lesions and on the risk for
- Differential scanning
calorimetric analysis showed that the free ABZ in the kneaded systems
existed in the amorphous state.
- Albendazole [ABZ;1
methyl(5-proylthio)1H-benzimidazole-2yl] carbamate is one of the most
important benzimidazole derivatives used against liver flukes,
tapeworms, and lung and gastrointestinal roundworms.
- Albendazole is an
effective treatment option for childhood giardiasis.
- Albendazole a
benzimidazole carbamate (methyl 5- propylthio-1H-benzimidazole-2-yl
carbamate) is a broad spectrum antiparasitic which is used worldwide
against a variety of parasites.
microspheres containing ABZ were prepared by emulsion/solvent
evaporation technique and characterized by scanning electron microscopy.
- A randomized trial
study was conducted comparing the efficacy of two high-dose regimens of
albendazole for the treatment of uncomplicated human
strongyloidiasis.Agar plate culture (APC) was used as an evaluation
technique for coprological diagnosis.
- In the Mechanism of
drug release from soild dispersion of albendazole, the perticle size of
drug is examined by noval dissolution technique.
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