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Aureofungin is a
heptaene type of antifungal antibiotic used for controlling plant fungal
infections and diseases, during pre and post harvesting period of
Polyene antibiotics are
known for their remarkable antifungal properties. The alkali metal and
quaternary alkylammonium salts of amphotericin B, nystatin and
aureofungin have been prepared by ion-exchange method.
and biological properties of these salts have been studied with a view
to evaluate their therapeutic advantages over the parent
aureofungin by Streptoverticillium cinnamoneum var, terricola was found
to be an oxygen dependent reaction. An accelerated rate of aureofungin
production, along with a better yield coefficient were obtained under
conditions of enhanced aeration during fermentation. A higher oxygen
transfer rate was found to stimulate aureofungin A, and suppresses
aureofungin B formation.
The widely used
agricultural antifungal agent aureofungin (ARF) was subjected to
genotoxicity assessment using the Ames Salmonella assay as well as the
in vivo micronucleus test and dominant lethal test in Swiss mice.
The root of coconut
gardens in Arsikere feeding with Aureofungin-sol (1.3%) + Bordeaux
mixture (1(Yo) soil drenching at quarterly interval along with soil
application of neem cake at 5 kg/palm/year was found to be most
effective in checking the disease.