comprise a family of three well-known industrially produced major, and
several rare, minor cyclic oligosaccharides. The three major CDs are
crystalline, homogeneous, nonhygroscopic substances, which are torus-like
macro-rings built up from glucopyranose units.
(CD) is synthesized by bacterial cyclodextrin glycosyl transferase (CG
Tase) and is widely used in food, pharmaceutical, cosmetic, and
The b- CD produced using
partially purified and crude CGTase were compared and found to have no
significant difference in yield and productivity. The appropriate
proportion of CG Tase to sago starch for b-CD production was determined
by response surface methodology.
and celecoxib in water. Phase-solubility studies were performed
according to the method reported by Higuchi and Connors.
cyclodextrin derivatives with
special substituents or substitution pattern, purification of CDs under
controlled cGMP conditions, cyclodextrin derivatives optimized for a
particular molecule substituted maltooligomers and special glucose
derivatives derived from cyclodextrins, cyclodextrin-assisted organic
syntheses, reproduction and evaluation of syntheses reported in the
literature, standardized preparation methods, scaling-up synthetic
procedures for the preparation of selected CD derivatives.
Cyclodextrin are used in food
formulations for flavour protection or flavour delivery. The major
benefits are stabilisation, odour control and process improvement upon
conversion of a liquid ingredient to a solid form. It can be used
extensively in Cosmetics, Agricultural and Chemical industries.
Dietary fibres are thought to support
gut health and may reduce the risk of coronary heart disease and other
diet-related disease. Nutritionists recommend a daily fibre intake of 25
- 30g but most people in the western world do not get enough fibre in
their daily diet.
cyclodextrin products, marketed under
the Cavamax brand name. The company, which generates annual sales of
€2.7 billion, also makes the Omega Dry omega oil powders and has
launched the first non-animal and non-human derived L-cysteine for the
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