- Ibogaine is a
naturally-occurring psychoactive compound found in a number of plants,
principally in a member of the dogbane family known as iboga.
preparations are used in medicinal and ritual purposes by African
spiritual traditions of the Bwiti who claim to have learned it from the
- In recent times it has
been identified as having anti-addictive properties. Ibogaine is an indole
alkaloid which is obtained either by extraction from the iboga plant or by
semi-synthesis from the precursor compound voacangine, another plant
- A full organic
synthesis of ibogaine has been achieved, but is too expensive and
challenging to produce any commercially significant yield.
- One of the first
noticeable effects of large-dose ibogaine ingestion is ataxia, a
difficulty in coordinating muscle motion which makes standing and walking
virtually impossible without assistance.
- Tabernanthe iboga, is a
plant that grows wild in forests around Africa.
- Tabernanthe Iboga is a
small shrub of the Apocynace family that grows principally in the
equatorial forests of Gabon, Guinea, the Congo and the Cameroon.
- The plant is a yellow
flowered bush between 1.5 - 2.0 meters in height.
- Its psychoactive
alkaloids are concentrated in the roots.
- The main active
component is ibogaine, an indole alkaloid.
- The alkaloids are
related to Ibogaine and as well as Tabernanthe iboga, and have the same
- The root bark of
Tabernanthe iboga contains ibogaine as its predominant alkaloid and has
been an important source of it.
- Ibogaine is used
experimentally to interrupt drug addiction and allow therapeutic
- Ibogaine is principally
recognised for its ability to vastly reduce the symptoms of drug
- The plant is used also
as a general stimulant, especially when a lot of effort or endurance is
required, such as on hunting expeditions, the root being chewed.
- Tabernaemontana in
South America and the closely related Tabernanthe iboga of central Africa
have been used in religious rituals to bring on visions of
ancestors, nature spirits, or distant places.
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