Hydrogenase                                                                                       Cultivation, Extraction, Effects and Treatment            
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                                         Information @ a Glance
  • Ibogaine is a naturally-occurring psychoactive compound found in a number of plants, principally in a member of the dogbane family known as iboga.
  • Ibogaine-containing preparations are used in medicinal and ritual purposes by African spiritual traditions of the Bwiti who claim to have learned it from the Pygmy.
  • In recent times it has been identified as having anti-addictive properties. Ibogaine is an indole alkaloid which is obtained either by extraction from the iboga plant or by semi-synthesis from the precursor compound voacangine, another plant alkaloid.
  • A full organic synthesis of ibogaine has been achieved, but is too expensive and challenging to produce any commercially significant yield.
  • One of the first noticeable effects of large-dose ibogaine ingestion is ataxia, a difficulty in coordinating muscle motion which makes standing and walking virtually impossible without assistance.
  • Tabernanthe iboga, is a plant that grows wild in forests around Africa.
  • Tabernanthe Iboga is a small shrub of the Apocynace family that grows principally in the equatorial forests of Gabon, Guinea, the Congo and the Cameroon.
  • The plant is a yellow flowered bush between 1.5 - 2.0 meters in height.
  •  Its psychoactive alkaloids are concentrated in the roots. 
  • The main active component is ibogaine, an indole alkaloid.
  • The alkaloids are related to Ibogaine and as well as Tabernanthe iboga, and have the same psychopharmacology.
  • The root bark of Tabernanthe iboga contains ibogaine as its predominant alkaloid and has been an important source of it.
  • Ibogaine is used experimentally to interrupt drug addiction and allow therapeutic intervention.
  • Ibogaine is principally recognised for its ability to vastly reduce the symptoms of drug withdrawal.
  • The plant is used also as a general stimulant, especially when a lot of effort or endurance is required, such as on hunting expeditions, the root being chewed.
  • Tabernaemontana in South America and the closely related Tabernanthe iboga of central Africa have been used in religious rituals  to bring on visions of ancestors, nature spirits, or distant places.

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