IV Fluids                                 

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Information @ a Glance


  • Intravenous fluids may be classified into crystalloids, colloids, and blood products (box).

  • Crystalloids are substances that form a true solution and pass freely through a semipermeable membrane.

  • Colloids are substances that do not dissolve into a true solution and do not pass through a semipermeable membrane.

  • The administration of intravenous fluids is one of the most common and universal interventions in medicine.

Production Process

  • Intravenous fluids can supply two things: fluid volume and electrolytes.

  • These fluids are usually provided to acutely expand intravascular volume, to correct an underlying imbalance in fluids or electrolytes or to compensate for an ongoing problem that is affecting either fluid or electrolytes.

  • Two IV solutions are used for acute volume expansio. They are Normal Saline (0.9%) and Lactated Ringer's Solution.

  • Normal Saline is nothing more than salt water at a concentration that is isotonic with the blood (154 mM sodium).

Medicinal Uses

  • Wide use of hypotonic IV solutions is for hydration therapy.

  • Chilled IV fluids can be much more effective for the induction of hypothermia than commonly assumed, but they must be administered
    very rapidly to avoid heat gains in IV tubing.

  • Management of intravenous (IV) fluids must be optimized perioperatively to avoid tissue hypoperfusion or fluid overload.

  • Warmed intravenous fluids used in hypothermic patients.


  • Field intravenous reconstitution (FIVR) is envisioned to be an integrated medical component system .

  • The above FIVR produces a variety of packaged IV fluids in large quantities to support field medical treatment facilities (MTF) that provide emergency resuscitative surgery and critical care.

  • The objective of FIVR is to design and develop an FDA-approved Environmental Protection Agency-quality water-source processing device consisting of integrated medical grade components.

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