- Lipitor is a
cholesterol-lowering medication that blocks the production of
cholesterol (a type of fat) in the body.
- LIPITOR® (atorvastatin
calcium) is a synthetic lipid-lowering agent. Atorvastatin is an
inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase.
- Atorvastatin calcium
is a white to off-white crystalline powder.
- Lipitor is used to
treat high cholesterol. Lipitor is also used to lower the risk of
stroke, heart attack, or other heart complications in people with
coronary heart disease or type 2 diabetes.
- Lipitor can cause a
condition that results in the breakdown of skeletal muscle tissue. This
condition can lead to kidney failure.
- Grapefruit and
grapefruit juice may interact with Lipitor and lead to potentially
- The US drug-maker
waged a protracted battle against companies making generic similars of
- Pfizer’s sales stand
to be hurt if generic companies managed to use provisions in the US law
to legally enter that market with generic Lipitor. The US market for
Lipitor is estimated at $8 billion, and that explains Pfizer’s efforts
to ward off any generic competition.
- Market exclusivity
and intellectual property-related battles notwithstanding, the
importance of medicines like Lipitor is their relevance to patients.
- Lipitor is the
world's largest-selling drug (2007 sales: $12.7 billion) and the delay
in the launch of the generic clone could help it save as much as $5
billion in profit, the analysts added. The Pfizer stock was down 0.16
per cent in early trade in New York.
- Lipitor’s blockbuster
revenue is seriously threatened by imminent patent expiration in some of
the drug’s largest markets such as the US, Japan and the UK, there is
significant unrest between Pfizer’s key stakeholders about the future of
- A union estimates 20
million Americans take statins and about 60 percent of people who take
brand-name statin drugs — Lipitor, Zocor, Vytorin and Crestor — can
safely use one of three generics
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