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Information @ a Glance


  • Lipitor is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body.
  • LIPITOR® (atorvastatin calcium) is a synthetic lipid-lowering agent. Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase.
  • Atorvastatin calcium is a white to off-white crystalline powder.
  • Lipitor is used to treat high cholesterol. Lipitor is also used to lower the risk of stroke, heart attack, or other heart complications in people with coronary heart disease or type 2 diabetes.
  • Lipitor can cause a condition that results in the breakdown of skeletal muscle tissue. This condition can lead to kidney failure.
  • Grapefruit and grapefruit juice may interact with Lipitor and lead to potentially dangerous effects.
  • The US drug-maker waged a protracted battle against companies making generic similars of Lipitor.
  • Pfizer’s sales stand to be hurt if generic companies managed to use provisions in the US law to legally enter that market with generic Lipitor. The US market for Lipitor is estimated at $8 billion, and that explains Pfizer’s efforts to ward off any generic competition.
  • Market exclusivity and intellectual property-related battles notwithstanding, the importance of medicines like Lipitor is their relevance to patients.
  • Lipitor is the world's largest-selling drug (2007 sales: $12.7 billion) and the delay in the launch of the generic clone could help it save as much as $5 billion in profit, the analysts added. The Pfizer stock was down 0.16 per cent in early trade in New York.
  • Lipitor’s blockbuster revenue is seriously threatened by imminent patent expiration in some of the drug’s largest markets such as the US, Japan and the UK, there is significant unrest between Pfizer’s key stakeholders about the future of the drug.
  • A union estimates 20 million Americans take statins and about 60 percent of people who take brand-name statin drugs — Lipitor, Zocor, Vytorin and Crestor — can safely use one of three generics

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