Metformin Hydrochloride is an anti-diabetic preparation.
Metformin hydrochloride is a white, crystalline powder which is
odourless or almost odourless and hygroscopic.
freely soluble in water, slightly soluble in ethanol (96%), and
practically insoluble in chloroform and ether.
chemical name for metformin hydrochloride is 1,1-dimethylbiguanide
Metformin is an oral biguanide hypoglycaemic agent.
Metformin is excreted unchanged in the urine and does not undergo
simple and rapid HPLC assay method for the estimation of metformin
in human plasma was developed and validated.
Extended release (ER) formulation of metformin hydrochloride (HCl)
investigates the possibility for development of a direct compression
ER matrix tablet using hypromellose.
synthesis, characterization and pharmacodynamic evaluation of the
copper [Cu2+] and nickel [Ni2+] complexes of metformin have been
may be used as initial treatment or in sulfonylurea failures either
alone or in combination with a sulfonylurea and other oral agents.
hydrochloride is an oral biguanidine, which reduces the elevated blood
glucose concentration in patients with diabetes but does not increase
hydrochloride is a high-dose drug widely used as an oral
size and improved release technology has evolved the therapy of
metformin. Thus, metformin still is used as a therapeutic agent of
first choice for monotherapy of the typical overweight patient.
simple, rapid and precise method is developed for the quantitative
simultaneous determination of metformin hydrochloride and
rosiglitazone maleate in a combined pharmaceutical-dosage form.
performance reverse phase liquid chromatographic procedure is
developed for the Simultaneous estimation of Metformin Hydrochloride
and Pioglitazone hydrochloride in combined tablet dosage form.
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