Metronidazole is an antibiotic used to treat different kinds of
Metronidazole is a nitroimidazole anti-infective medication used mainly in
the treatment of infections caused by susceptible organisms, particularly
anaerobic bacteria and protozoa.
Metronidazole is a prodrug,It is converted in anaerobic organisms by the
redox enzyme pyruvate-ferredoxin oxidoreductase.
- The nitro
group of metronidazole is chemically reduced by ferredoxin and the
products are responsible for disrupting the DNA helical structure, thus
inhibiting nucleic acid synthesis.
Metronidazole marketed by Pfizer under the trade name Flagyl in the US,
while Sanofi-Aventis markets metronidazole globally under the same trade
name, Flagyl, and also by various generic manufacturers, who sell it
at a lower price.
Metronidazole has also been used in women to prevent preterm birth
associated with bacterial vaginosis, amongst other risk factors including
the presence of cervicovaginal fetal fibronectin.
randomised controlled trial demonstrated that metronidazole was
ineffective in preventing preterm delivery in high-risk pregnant women
and, conversely, the incidence of preterm delivery was actually higher in
women treated with metronidazole.
Entrepreneur who want the
information on Product, Process,
Market, Msds, Patent, Consultants, Application Can E-Mail us to