- Paracetamol (INN) or
acetaminophen (USAN) is a widely-used analgesic and antipyretic.
- Paracetamol has been
in use as an analgesic for home medication for over 30 years.
- The effectiveness of
paracetamol was discovered without knowing how it works.
- The proposed
mechanism for an interaction between paracetamol use and asthma,
depletion of glutathione in lung tissue, was criticised as 'biologically
- Paracetamol is
primarily metabolised by the liver.
- Paracetamol and its
two primary metabolites are remarkably safe compounds, and the
hepatotoxicity of paracetamol arises only through the 5% that is
Paracetamol manufacture via Nitro Benzene route is yet
to start in the country.
- Paracetamol has not
been shown to cause asthma and remains the analgesic of choice for
people with asthma.
- Paracetamol relieves
pain and fever in adults and children, and is the most widely accepted
medicine in the UK for this purpose.
- Paracetamol can be
combined with decongestant ingredients to help relieve the symptoms of
the common cold, influenza and sinusitis by relieving headache, general
aches, nasal congestion and fever.
- Paracetamol may
protect against cardiovascular disease.
The total world market for
Paracetamol bulk drug is estimated to be about 1,10,000 tonnes per
annum, with Europe and North America accounting for nearly 40% of the
USA, Germany, Turkey, China and
India are the leading producers of Paracetamol bulk drug.
The domestic market for
paracetamol has grown substantially in the last decade.
Exports of paracetamol is likely
to grow at an average annual growth rate of 15% considering the
tremendous scope that exists for export of paracetamol.
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