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  • Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. Piperazine exists as small alkaline deliquescent crystals with a saline taste.
  • The piperazines are a broad class of chemical compounds, many with important pharmacological properties, which contain a core piperazine functional group.
  • Piperazines were originally named because of their chemical similarity with piperidine, a structural constituent of piperine in the black pepper plant.
  • Piperazines are also used in the manufacture of plastics, resins, pesticides, brake fluid and other industrial materials.
  • To determine the efficiency of an ionic liquid as a catalytic medium in polyimide synthesis, a piperazine based monomer was chosen as a model compound.
  • Piperazine is freely soluble in water and ethylene glycol, but insoluble in diethyl ether.
  • Piperazine was introduced to medicine as a solvent for uric acid.
  • When Piperazine was taken into the body the drug is partly oxidized and partly eliminated unchanged.
  • Piperazine ferulate tablets are used as a Chinese herb and in one patient resulted in elevated liver enzymes when taken during treatment for latent tuberculosis infection with isoniazid.

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