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  • Thiram is a non-systemic dimethyl dithiocarbamate fungicide.
  • Thiram is white or yellow crystalline solid with a characteristic odor at room temperature.
  • Thiram is a peptizing agent in sulfur-modified polychloroprenes.
  • Thiram is available in dust, flowable, wettable powder, water dispersible granules, and water suspension formulations.
  • Thiram is not persistent in soils and also is nearly immobile in clay or highly organic soils.


  • The intracellular oxidation of dimethyldithiocarbamate anions to thiram, which in turn oxidizes intracellular glutathione(GSH).
  • The metabolic interconversion of thiram and dimethyldithiocarbamic acid and the biochemical pathway may control the metabolic fate of compounds in S. cerevisiae.
  • Thiram-tetramethylthiuram disulphide a chelator of heavy metals, inhibited DNA synthesis and induced apoptosis in cultured bovine capillary endothelial cells.
  • The isolation and primary characterization of microbial species obtained from enrichment soil cultures capable of utilizing tetramethylthiuram disulfide(TMTD).


  • Thiram [bis(dimethylthiocarbamoyl) disulfide] was one of the first dithiocarbamate fungicides used for the control of plant diseases.
  • Thiram, tetramethyl thiuram disulphide an organic sulphur compound is a fungicide commonly used for treating corn and other grains intended for seed purposes and also for storing food grains.
  • Soil samples treated with thiram, eptam or vernam yielded secondary amines, but no nitrosamines.
  • A fungicide with Tirama agent was applied to the two different economically important culture species of corn (Zea mays L.) in different concentrations and morphological and physiological effects of this fungicide on seedlings grown from seeds were analyzed.


  • TMTD[tetramethylthiuram disulfide]-degrading microorganisms were isolated by the enrichment and adaptation techniques.
  • HPLC is the most preferred analytical technique used in pesticide analysis. The analysis of thiram formulations and technical products has been carried out by HPLC using methanol.
  • A number of techniques such as Spectrophotometric1, chromatography2, voltammetric3, polarographic4, capillary electrophoretic5, etc., has been used for the detection and analysis of thiram.
  • Thiram found on silver surface can be determined by surface enhanced Raman scattering(SERS) technique.

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